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Vascular Endothelial Growth Factor-Mediated Autocrine Stimulation of Prostate Tumor Cells Coincides with Progression to a Malignant Phenotype

Vascular endothelial growth factor (VEGF), which is often produced at high levels by tumor cells, is a well-known mediator of tumor angiogenesis. VEGF receptor tyrosine kinases, KDR/Flk-1 and Flt-1, have been thought to be expressed exclusively by endothelial cells. In this study, we have used a pro...

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Detalhes bibliográficos
Main Authors: Soker, Shay, Kaefer, Martin, Johnson, Michelle, Klagsbrun, Michael, Atala, Anthony, Freeman, Michael R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850559/
https://ncbi.nlm.nih.gov/pubmed/11485923
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