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Sepsis-Induced Apoptosis Leads to Active Suppression of Delayed-Type Hypersensitivity by CD8(+) Regulatory T Cells through a TRAIL-Dependent Mechanism

Patients who survive severe sepsis often display severely compromised immune function. One hallmark of such immune suppression in septic patients is an impaired delayed-type hypersensitivity (DTH) response, manifested by a loss of skin testing to recall Ags. Because sepsis induces significant apopto...

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書誌詳細
主要な著者: Unsinger, Jacqueline, Kazama, Hirotaka, McDonough, Jacqueline S., Griffith, Thomas S., Hotchkiss, Richard S., Ferguson, Thomas A.
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2887093/
https://ncbi.nlm.nih.gov/pubmed/20483771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0904054
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