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Sepsis-Induced Apoptosis Leads to Active Suppression of Delayed-Type Hypersensitivity by CD8(+) Regulatory T Cells through a TRAIL-Dependent Mechanism
Patients who survive severe sepsis often display severely compromised immune function. One hallmark of such immune suppression in septic patients is an impaired delayed-type hypersensitivity (DTH) response, manifested by a loss of skin testing to recall Ags. Because sepsis induces significant apopto...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2887093/ https://ncbi.nlm.nih.gov/pubmed/20483771 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0904054 |
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