Cathepsin B Is the Driving Force of Esophageal Cell Invasion in a Fibroblast-Dependent Manner

Esophageal cancer, which frequently exhibits coordinated loss of E-cadherin (Ecad) and transforming growth factor β (TGFβ) receptor II (TβRII), has a high mortality rate. In a three-dimensional organotypic culture model system, esophageal keratinocytes expressing dominant-negative mutant versions of...

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Hauptverfasser: Andl, Claudia D, McCowan, Kelsey M, Allison, Gillian L, Rustgi, Anil K
Format: Artigo
Sprache:Inglês
Veröffentlicht: Neoplasia Press Inc. 2010
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2887089/
https://ncbi.nlm.nih.gov/pubmed/20563251
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