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Genetic and Epigenetic Regulation and Expression Signatures of Glutathione S-Transferases in Developing Mouse Liver

The hepatic glutathione S-transferases (Gsts) are critical phase II enzymes in protecting cellular macromolecules against electrophiles and oxidative stress. Little is known about the ontogeny of Gsts and the underlying regulatory mechanisms during liver development. Therefore, in this study, the on...

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Detalhes bibliográficos
Main Authors: Cui, Julia Yue, Choudhuri, Supratim, Knight, Tamara R., Klaassen, Curtis D.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2886863/
https://ncbi.nlm.nih.gov/pubmed/20395309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfq115
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