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Induction of Hepatic Glutathione S-Transferases in Male Mice by Prototypes of Various Classes of Microsomal Enzyme Inducers

The underlying need for glutathione S-transferase (Gst) induction is thought to be an adaptive response to chemical stress within the cell. Classical microsomal enzyme inducers (MEIs) increase the expression of biotransformation enzymes (phase I and II) and transporters through transcription factors...

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Detalhes bibliográficos
Main Authors: Knight, Tamara R., Choudhuri, Supratim, Klaassen, Curtis D.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2581675/
https://ncbi.nlm.nih.gov/pubmed/18723825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfn179
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