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A C. elegans eIF4E-family member upregulates translation at elevated temperatures of mRNAs encoding MSH-5 and other meiotic crossover proteins

Caenorhabditis elegans expresses five family members of the translation initiation factor eIF4E whose individual physiological roles are only partially understood. We report a specific role for IFE-2 in a conserved temperature-sensitive meiotic process. ife-2 deletion mutants have severe temperature...

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Hlavní autoři: Song, Anren, Labella, Sara, Korneeva, Nadejda L., Keiper, Brett D., Aamodt, Eric J., Zetka, Monique, Rhoads, Robert E.
Médium: Artigo
Jazyk:Inglês
Vydáno: Company of Biologists 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2886744/
https://ncbi.nlm.nih.gov/pubmed/20530576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.063107
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