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Roles for Nox4 in the contractile response of bovine pulmonary arteries to hypoxia

Hypoxia appears to promote contraction [hypoxic pulmonary vasoconstriction (HPV)] of bovine pulmonary arteries (BPA) through removal of a peroxide-mediated relaxation. This study examines the roles of BPA Nox oxidases and mitochondria in the HPV response. Inhibitors of Nox2 (0.1 mM apocynin and 50 μ...

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Detalhes bibliográficos
Main Authors: Ahmad, Mansoor, Kelly, Melissa R., Zhao, Xiangmin, Kandhi, Sharath, Wolin, Michael S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2886632/
https://ncbi.nlm.nih.gov/pubmed/20304813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.01228.2009
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