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Mitochondrial-derived hydrogen peroxide inhibits relaxation of bovine coronary arterial smooth muscle to hypoxia through stimulation of ERK MAP kinase

Mitochondrial reactive oxygen species (ROS) are potentially important in vascular oxygen-sensing mechanisms because hypoxia appears to be a stimulus for mitochondrial ROS generation; however, scavenging of endogenous ROS does not alter relaxation of endothelium-denuded bovine coronary arteries (BCA)...

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Detalhes bibliográficos
Main Authors: Gao, Qun, Zhao, Xiangmin, Ahmad, Mansoor, Wolin, Michael S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2793133/
https://ncbi.nlm.nih.gov/pubmed/19855056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00817.2009
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