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Targeted deletion of NF-κB p50 diminishes the cardioprotection of histone deacetylase inhibition

We have recently demonstrated that the inhibition of histone deacetylases (HDAC) protects the heart against ischemia-reperfusion (I/R) injury. The mechanism by which HDAC inhibition confers myocardial protection remains unknown. The purpose of this study is to investigate whether the disruption of N...

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Autori principali: Zhang, L. X., Zhao, Y., Cheng, G., Guo, T. L., Chin, Y. E., Liu, P. Y., Zhao, T. C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2886620/
https://ncbi.nlm.nih.gov/pubmed/20382965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.01015.2009
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