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Fibroblast-specific expression of AC6 enhances β-adrenergic and prostacyclin signaling and blunts bleomycin-induced pulmonary fibrosis

Pulmonary fibroblasts regulate extracellular matrix production and degradation and are critical in maintenance of lung structure, function, and repair, but they also play a central role in lung fibrosis. cAMP-elevating agents inhibit cytokine- and growth factor-stimulated myofibroblast differentiati...

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Detalhes bibliográficos
Main Authors: Liu, Xiaoqiu, Li, Fengying, Sun, Shu Qiang, Thangavel, Muthusamy, Kaminsky, Joseph, Balazs, Louisa, Ostrom, Rennolds S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2886616/
https://ncbi.nlm.nih.gov/pubmed/20348281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00429.2009
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