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A prostacyclin analogue, iloprost, protects from bleomycin-induced pulmonary fibrosis in mice
BACKGROUND: Metabolites of arachidonic acid such as prostacyclin (PGI(2)) have been shown to participate in the pathogenesis of pulmonary fibrosis by inhibiting the expression of pro-inflammatory and pro-fibrotic mediators. In this investigation, we examined whether iloprost, a stable PGI(2 )analogu...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2848635/ https://ncbi.nlm.nih.gov/pubmed/20302663 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-11-34 |
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