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Identification of triptolide, a natural diterpenoid compound, as an inhibitor of lung inflammation

Inflammation is associated with various pulmonary diseases and contributes to the pathogenesis of acute lung injury. We previously identified a proinflammatory signaling pathway triggered by G protein-coupled receptors (GPCRs) in which stimulation of G(q)-coupled GPCRs results in activation of the t...

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Autori principali: Hoyle, Gary W., Hoyle, Christine I., Chen, Jing, Chang, Weiyuan, Williams, Ronald W., Rando, Roy J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2886612/
https://ncbi.nlm.nih.gov/pubmed/20348278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00014.2010
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