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Zinc modulates the innate immune response in vivo to polymicrobial sepsis through regulation of NF-κB

Zinc is an essential element that facilitates coordination of immune activation during the host response to infection. We recently reported that zinc deficiency increases systemic inflammation, vital organ damage, and mortality in a small animal model of sepsis. To investigate potential mechanisms t...

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Bibliographic Details
Main Authors: Bao, Shengying, Liu, Ming-Jie, Lee, Bryan, Besecker, Beth, Lai, Ju-Ping, Guttridge, Denis C., Knoell, Daren L.
Format: Artigo
Language:Inglês
Published: American Physiological Society 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2886607/
https://ncbi.nlm.nih.gov/pubmed/20207754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00368.2009
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