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Skeletal muscle protein balance in mTOR heterozygous mice in response to inflammation and leucine

Sepsis and lipopolysaccharide (LPS) may decrease skeletal muscle protein synthesis by impairing mTOR (mammalian target of rapamycin) activity. The role of mTOR in regulating muscle protein synthesis was assessed in wild-type (WT) and mTOR heterozygous (+/−) mice under basal conditions and in respons...

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Autors principals: Lang, Charles H., Frost, Robert A., Bronson, Sarah K., Lynch, Christopher J., Vary, Thomas C.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2886531/
https://ncbi.nlm.nih.gov/pubmed/20388826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00676.2009
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