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Transmembrane TNF-α: structure, function and interaction with anti-TNF agents
Transmembrane TNF-α, a precursor of the soluble form of TNF-α, is expressed on activated macrophages and lymphocytes as well as other cell types. After processing by TNF-α-converting enzyme (TACE), the soluble form of TNF-α is cleaved from transmembrane TNF-α and mediates its biological activities t...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2886310/ https://ncbi.nlm.nih.gov/pubmed/20194223 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/rheumatology/keq031 |
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