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Inventory of the Human Mitochondrial Gene Expression Machinery with Links to Disease

Mammalian mitochondrial DNA encodes thirty-seven essential genes required for ATP production via oxidative phosphorylation, instability or misregulation of which is associated with human diseases and aging. Other than the mtDNA-encoded RNA species (thirteen mRNAs, 12S and 16S rRNAs, and twenty-two t...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Shutt, Timothy E., Shadel, Gerald S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2886302/
https://ncbi.nlm.nih.gov/pubmed/20544879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/em.20571
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