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Inventory of the Human Mitochondrial Gene Expression Machinery with Links to Disease

Mammalian mitochondrial DNA encodes thirty-seven essential genes required for ATP production via oxidative phosphorylation, instability or misregulation of which is associated with human diseases and aging. Other than the mtDNA-encoded RNA species (thirteen mRNAs, 12S and 16S rRNAs, and twenty-two t...

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Detalhes bibliográficos
Main Authors: Shutt, Timothy E., Shadel, Gerald S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2886302/
https://ncbi.nlm.nih.gov/pubmed/20544879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/em.20571
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