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Evaluation of endogenous acidic metabolic products associated with carbohydrate metabolism in tumor cells

Tumor cells have a high tolerance for acidic and hypoxic microenvironments, also producing abundant lactic acid through accelerated glycolysis in the presence or absence of O(2). While the accumulation of lactate is thought to be a major contributor to the reduction of pH-circumscribing aggressive t...

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Detalhes bibliográficos
Main Authors: Mazzio, Elizabeth A., Smith, Bruce, Soliman, Karam F. A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2886276/
https://ncbi.nlm.nih.gov/pubmed/19784859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10565-009-9138-6
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