Inhibition of Neovascularization to Simultaneously Ameliorate Graft-vs-Host Disease and Decrease Tumor Growth

BACKGROUND: Blood vessels are formed either by sprouting of resident tissue endothelial cells (angiogenesis) or by recruitment of bone marrow (BM)–derived circulating endothelial progenitor cells (EPCs, vasculogenesis). Neovascularization has been implicated in tumor growth and inflammation, but its...

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Autori principali: Penack, Olaf, Henke, Erik, Suh, David, King, Chris G., Smith, Odette M., Na, Il-Kang, Holland, Amanda M., Ghosh, Arnab, Lu, Sydney X., Jenq, Robert R., Liu, Chen, Murphy, George F., Lu, Theresa T., May, Chad, Scheinberg, David A., Gao, Ding Cheng, Mittal, Vivek, Heller, Glenn, Benezra, Robert, van den Brink, Marcel R. M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2010
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2886094/
https://ncbi.nlm.nih.gov/pubmed/20463307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djq172
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