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Dynamic link of DNA demethylation, DNA strand breaks and repair in mouse zygotes
In mammalian zygotes, the 5-methyl-cytosine (5mC) content of paternal chromosomes is rapidly changed by a yet unknown but presumably active enzymatic mechanism. Here, we describe the developmental dynamics and parental asymmetries of DNA methylation in relation to the presence of DNA strand breaks,...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2885932/ https://ncbi.nlm.nih.gov/pubmed/20442707 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.80 |
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