Farnesylation of Retinal Transducin Underlies Its Translocation during Light Adaptation

G proteins are posttranslationally modified by isoprenylation: either farnesylation or geranylgeranylation. The γ subunit of retinal transducin (Tα/Tβγ) is selectively farnesylated, and the farnesylation is required for light signaling mediated by transducin in rod cells. However, whether and how th...

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Hauptverfasser: Kassai, Hidetoshi, Aiba, Atsu, Nakao, Kazuki, Nakamura, Kenji, Katsuki, Motoya, Xiong, Wei-Hong, Yau, King-Wai, Imai, Hiroo, Shichida, Yoshinori, Satomi, Yoshinori, Takao, Toshifumi, Okano, Toshiyuki, Fukada, Yoshitaka
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2005
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885908/
https://ncbi.nlm.nih.gov/pubmed/16102536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2005.07.025
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