Impaired Channel Targeting and Retinal Degeneration in Mice Lacking the Cyclic Nucleotide-Gated Channel Subunit CNGB1

Cyclic nucleotide-gated (CNG) channels are important mediators in the transduction pathways of rod and cone photoreceptors. Native CNG channels are heterotetramers composed of homologous A and B subunits. In heterologous expression systems, B subunits alone cannot form functional CNG channels, but t...

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Bibliographic Details
Main Authors: Hüttl, Sabine, Michalakis, Stylianos, Seeliger, Mathias, Luo, Dong-Gen, Acar, Niyazi, Geiger, Heidi, Hudl, Kristiane, Mader, Robert, Haverkamp, Silke, Moser, Markus, Pfeifer, Alexander, Gerstner, Andrea, Yau, King-Wai, Biel, Martin
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2005
Subjects:
Cellular/Molecular
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885903/
https://ncbi.nlm.nih.gov/pubmed/15634774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3764-04.2005
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