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Distinct patterns of DNA copy number alterations associate with BRAF mutations in melanomas and melanoma derived cell lines
A majority of malignant melanomas harbor an oncogenic mutation in either BRAF or NRAS. If BRAF and NRAS transform melanoma cells by a similar mechanism, then additional genetic aberrations would be similar (or random). Alternatively, distinct mutation-associated changes would suggest the existence o...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2885833/ https://ncbi.nlm.nih.gov/pubmed/19226609 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gcc.20651 |
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