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Maintenance and termination of neocortical oscillations by dynamic modulation of intrinsic and synaptic excitability

Mechanisms underlying seizure cessation remain elusive. The Lennox-Gastaut syndrome, a severe childhood epileptic disorder, is characterized by episodes of seizure with alternating epochs of spike-wave and fast run discharges. In a detailed computational model that incorporates extracellular potassi...

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Bibliographic Details
Main Authors: FRÖHLICH, FLAVIO, BAZHENOV, MAXIM, TIMOFEEV, IGOR, SEJNOWSKI, TERRENCE J.
Format: Artigo
Language:Inglês
Published: 2005
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885743/
https://ncbi.nlm.nih.gov/pubmed/20556224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/S147292880700015
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