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Pathological Effect of Homeostatic Synaptic Scaling on Network Dynamics in Diseases of the Cortex

Slow periodic EEG discharges are common in CNS disorders. The pathophysiology of this aberrant rhythmic activity is poorly understood. We used a computational model of a neocortical network with a dynamic homeostatic scaling rule to show that loss of input (partial deafferentation) can trigger netwo...

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Detalhes bibliográficos
Main Authors: Fröhlich, Flavio, Bazhenov, Maxim, Sejnowski, Terrence J.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2882860/
https://ncbi.nlm.nih.gov/pubmed/18272691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4263-07.2008
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