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Pathological Effect of Homeostatic Synaptic Scaling on Network Dynamics in Diseases of the Cortex
Slow periodic EEG discharges are common in CNS disorders. The pathophysiology of this aberrant rhythmic activity is poorly understood. We used a computational model of a neocortical network with a dynamic homeostatic scaling rule to show that loss of input (partial deafferentation) can trigger netwo...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Society for Neuroscience
2008
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2882860/ https://ncbi.nlm.nih.gov/pubmed/18272691 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4263-07.2008 |
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