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CXCL9 and CXCL10 are Antagonistic Costimulation Molecules During the Priming of Alloreactive T cell Effectors
Donor antigen-reactive CD4 and CD8 T cell production of interferon (IFN)-γ is a principal effector mechanism promoting tissue injury during allograft rejection. The CXCR3-binding chemokines CXCL9 and CXCL10 recruit donor-reactive T cells to the allograft, but their role during priming of donor-react...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2885704/ https://ncbi.nlm.nih.gov/pubmed/20194716 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0903831 |
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