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CXCL9 and CXCL10 are Antagonistic Costimulation Molecules During the Priming of Alloreactive T cell Effectors

Donor antigen-reactive CD4 and CD8 T cell production of interferon (IFN)-γ is a principal effector mechanism promoting tissue injury during allograft rejection. The CXCR3-binding chemokines CXCL9 and CXCL10 recruit donor-reactive T cells to the allograft, but their role during priming of donor-react...

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Bibliografiset tiedot
Päätekijät: Rosenblum, Joshua M., Shimoda, Naohiko, Schenk, Austin D., Zhang, Howard, Kish, Danielle D., Keslar, Karen, Farber, Joshua M., Fairchild, Robert L.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885704/
https://ncbi.nlm.nih.gov/pubmed/20194716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0903831
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