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A novel phosphatase cascade regulates differentiation in Trypanosoma brucei via a glycosomal signaling pathway
In the mammalian bloodstream, the sleeping sickness parasite Trypanosoma brucei is held poised for transmission by the activity of a tyrosine phosphatase, TbPTP1. This prevents differentiation of the transmissible “stumpy forms” until entry into the tsetse fly, whereupon TbPTP1 is inactivated and ma...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Cold Spring Harbor Laboratory Press
2010
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2885665/ https://ncbi.nlm.nih.gov/pubmed/20551176 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.570310 |
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