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A novel phosphatase cascade regulates differentiation in Trypanosoma brucei via a glycosomal signaling pathway

In the mammalian bloodstream, the sleeping sickness parasite Trypanosoma brucei is held poised for transmission by the activity of a tyrosine phosphatase, TbPTP1. This prevents differentiation of the transmissible “stumpy forms” until entry into the tsetse fly, whereupon TbPTP1 is inactivated and ma...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Szöőr, Balázs, Ruberto, Irene, Burchmore, Richard, Matthews, Keith R.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Cold Spring Harbor Laboratory Press 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885665/
https://ncbi.nlm.nih.gov/pubmed/20551176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.570310
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