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Calcineurin signaling and PGC-1α expression are suppressed during muscle atrophy due to diabetes
PGC-1α is a transcriptional coactivator that controls energy homeostasis through regulation of glucose and oxidative metabolism. Both PGC-1α expression and oxidative capacity are decreased in skeletal muscle of patients and animals undergoing atrophy, suggesting that PGC-1α participates in the regul...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2885580/ https://ncbi.nlm.nih.gov/pubmed/20359506 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2010.03.019 |
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