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Calcineurin signaling and PGC-1α expression are suppressed during muscle atrophy due to diabetes

PGC-1α is a transcriptional coactivator that controls energy homeostasis through regulation of glucose and oxidative metabolism. Both PGC-1α expression and oxidative capacity are decreased in skeletal muscle of patients and animals undergoing atrophy, suggesting that PGC-1α participates in the regul...

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Bibliografiske detaljer
Main Authors: Roberts-Wilson, Tiffany K., Reddy, Ramesh N., Bailey, James L., Zheng, Bin, Ordas, Ronald, Gooch, Jennifer L., Price, S. Russ
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885580/
https://ncbi.nlm.nih.gov/pubmed/20359506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2010.03.019
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