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Mechanism of U-insertion RNA Editing in Trypanosome Mitochondria: Characterization of RET2 Functional Domains by Mutational Analysis
The 3′ terminal uridylyl transferases (TUTases) selectively bind UTP and catalyze the addition of UMP to the 3′ hydroxyl of RNA substrates in a template-independent manner. RNA Editing TUTase 1 (RET1) and 2 (RET2) play central roles in uridine insertion/deletion RNA editing, which is an essential pa...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2010
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2885561/ https://ncbi.nlm.nih.gov/pubmed/20417643 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.04.035 |
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