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Mechanism of U-insertion RNA Editing in Trypanosome Mitochondria: Characterization of RET2 Functional Domains by Mutational Analysis

The 3′ terminal uridylyl transferases (TUTases) selectively bind UTP and catalyze the addition of UMP to the 3′ hydroxyl of RNA substrates in a template-independent manner. RNA Editing TUTase 1 (RET1) and 2 (RET2) play central roles in uridine insertion/deletion RNA editing, which is an essential pa...

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Detalhes bibliográficos
Main Authors: Ringpis, Gene-Errol, Stagno, Jason, Aphasizhev, Ruslan
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885561/
https://ncbi.nlm.nih.gov/pubmed/20417643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.04.035
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