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Mechanism of U-insertion RNA Editing in Trypanosome Mitochondria: The Bimodal TUTase Activity of the Core Complex

Expression of the trypanosomal mitochondrial genome requires the insertion and deletion of uridylyl residues at specific sites in pre-mRNAs. RET2 terminal uridylyl transferase (TUTase) is an integral component of the RNA editing core complex (RECC) and is responsible for the guide RNA-dependent U-in...

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Autors principals: Ringpis, Gene-Errol, Aphasizheva, Inna, Wang, Xiaorong, Huang, Lan, Lathrop, Richard H., Hatfield, G. Wesley, Aphasizhev, Ruslan
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885523/
https://ncbi.nlm.nih.gov/pubmed/20362585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.03.050
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