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Inhibition of Matrix Metalloproteinase Activity Prevents Increases in Myocardial Tumor Necrosis Factor-α

AIM: TNF-α is known to cause adverse myocardial remodeling. While we have previously shown a role for cardiac mast cells in mediating myocardial TNF-α, matrix metalloproteinases (MMP) activation of TNF-α may also be contributory. We sought to determine the relative roles of MMPs and cardiac mast cel...

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Detalhes bibliográficos
Main Authors: Murray, David B., Levick, Scott P, Brower, Gregory L., Janicki, Joseph S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885505/
https://ncbi.nlm.nih.gov/pubmed/20403361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2010.04.005
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