The actin cytoskeleton inhibits pore expansion during PIV5 fusion protein-promoted cell-cell fusion

Paramyxovirus fusion (F) proteins promote both virus-cell fusion, required for viral entry, and cell-cell fusion, resulting in syncytia formation. We used the F-actin stabilizing drug, jasplakinolide, and the G-actin sequestrant, latrunculin A, to examine the role of actin dynamics in cell-cell fusi...

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Bibliografiske detaljer
Main Authors: Wurth, Mark A., Schowalter, Rachel M., Smith, Everett Clinton, Moncman, Carole L., Dutch, Rebecca Ellis, McCann, Richard O.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885465/
https://ncbi.nlm.nih.gov/pubmed/20537366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2010.04.024
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