Molecular Basis of Alternating Access Membrane Transport by the Sodium-Hydantoin Transporter, Mhp1

The structure of the sodium-benzylhydantoin transport protein, Mhp1, from Microbacterium liquefaciens comprises a 5-helix inverted repeat, which is widespread amongst secondary transporters. Here we report the crystal structure of an inward-facing conformation of Mhp1 at 3.8 Å resolution, complement...

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Autores principales: Shimamura, Tatsuro, Weyand, Simone, Beckstein, Oliver, Rutherford, Nicholas G., Hadden, Jonathan M., Sharples, David, Sansom, Mark S.P., Iwata, So, Henderson, Peter J. F., Cameron, Alexander D.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885435/
https://ncbi.nlm.nih.gov/pubmed/20413494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1186303
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