Plasmacytoid Dendritic Cells Accumulate and Secrete Interferon Alpha in Lymph Nodes of HIV-1 Patients

Circulating plasmacytoid dendritic cells (pDC) decline during HIV-1 infection, but at the same time they express markedly higher levels of interferon alpha (IFNα), which is associated with HIV-1 disease progression. Here we show an accumulation of pDC in lymph nodes (LN) of treatment-naïve HIV-1 pat...

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Detalhes bibliográficos
Main Authors: Lehmann, Clara, Lafferty, Mark, Garzino-Demo, Alfredo, Jung, Norma, Hartmann, Pia, Fätkenheuer, Gerd, Wolf, Jeffrey S., van Lunzen, Jan, Romerio, Fabio
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885422/
https://ncbi.nlm.nih.gov/pubmed/20559432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011110
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