Multiple M. tuberculosis Phenotypes in Mouse and Guinea Pig Lung Tissue Revealed by a Dual-Staining Approach

A unique hallmark of tuberculosis is the granulomatous lesions formed in the lung. Granulomas can be heterogeneous in nature and can develop a necrotic, hypoxic core which is surrounded by an acellular, fibrotic rim. Studying bacilli in this in vivo microenvironment is problematic as Mycobacterium t...

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Autors principals: Ryan, Gavin J., Hoff, Donald R., Driver, Emily R., Voskuil, Martin I., Gonzalez-Juarrero, Mercedes, Basaraba, Randall J., Crick, Dean C., Spencer, John S., Lenaerts, Anne J.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2010
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885421/
https://ncbi.nlm.nih.gov/pubmed/20559431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011108
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