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Pantothenate Kinase 1 Is Required to Support the Metabolic Transition from the Fed to the Fasted State
Coenzyme A (CoA) biosynthesis is regulated by the pantothenate kinases (PanK), of which there are four active isoforms. The PanK1 isoform is selectively expressed in liver and accounted for 40% of the total PanK activity in this organ. CoA synthesis was limited using a Pank1 (−/−) knockout mouse mod...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2885419/ https://ncbi.nlm.nih.gov/pubmed/20559429 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011107 |
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