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The evolutionary impact of androgen levels on prostate cancer in a multi-scale mathematical model

BACKGROUND: Androgens bind to the androgen receptor (AR) in prostate cells and are essential survival factors for healthy prostate epithelium. Most untreated prostate cancers retain some dependence upon the AR and respond, at least transiently, to androgen ablation therapy. However, the relationship...

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Hlavní autoři: Eikenberry, Steffen E, Nagy, John D, Kuang, Yang
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885348/
https://ncbi.nlm.nih.gov/pubmed/20406442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1745-6150-5-24
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