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The evolutionary impact of androgen levels on prostate cancer in a multi-scale mathematical model

BACKGROUND: Androgens bind to the androgen receptor (AR) in prostate cells and are essential survival factors for healthy prostate epithelium. Most untreated prostate cancers retain some dependence upon the AR and respond, at least transiently, to androgen ablation therapy. However, the relationship...

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Detalhes bibliográficos
Main Authors: Eikenberry, Steffen E, Nagy, John D, Kuang, Yang
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885348/
https://ncbi.nlm.nih.gov/pubmed/20406442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1745-6150-5-24
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