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Timing, Coordination, and Rhythm: Acrobatics at the DNA Replication Fork
In DNA replication, the antiparallel nature of the parental duplex imposes certain constraints on the activity of the DNA polymerases that synthesize new DNA. The leading-strand polymerase advances in a continuous fashion, but the lagging-strand polymerase is forced to restart at short intervals. In...
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| Main Authors: | , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Biochemistry and Molecular Biology
2010
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2885174/ https://ncbi.nlm.nih.gov/pubmed/20382733 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R109.022939 |
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