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Timing, Coordination, and Rhythm: Acrobatics at the DNA Replication Fork

In DNA replication, the antiparallel nature of the parental duplex imposes certain constraints on the activity of the DNA polymerases that synthesize new DNA. The leading-strand polymerase advances in a continuous fashion, but the lagging-strand polymerase is forced to restart at short intervals. In...

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Hlavní autoři: Hamdan, Samir M., van Oijen, Antoine M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885174/
https://ncbi.nlm.nih.gov/pubmed/20382733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R109.022939
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