Transgenic mice expressing high plasma concentrations of human apolipoprotein B100 and lipoprotein(a).

The B apolipoproteins, apo-B48 and apo-B100, are key structural proteins in those classes of lipoproteins considered to be atherogenic [e.g., chylomicron remnants, beta-VLDL, LDL, oxidized LDL, and Lp(a)]. Here we describe the development of transgenic mice expressing high levels of human apo-B48 an...

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Détails bibliographiques
Auteurs principaux: Linton, M F, Farese, R V, Chiesa, G, Grass, D S, Chin, P, Hammer, R E, Hobbs, H H, Young, S G
Format: Artigo
Langue:Inglês
Publié: 1993
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC288508/
https://ncbi.nlm.nih.gov/pubmed/8254057
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