Transgenic mice expressing high plasma concentrations of human apolipoprotein B100 and lipoprotein(a).

The B apolipoproteins, apo-B48 and apo-B100, are key structural proteins in those classes of lipoproteins considered to be atherogenic [e.g., chylomicron remnants, beta-VLDL, LDL, oxidized LDL, and Lp(a)]. Here we describe the development of transgenic mice expressing high levels of human apo-B48 an...

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Detalles Bibliográficos
Publicado en:J Clin Invest
Autores principales: Linton, M F, Farese, R V, Chiesa, G, Grass, D S, Chin, P, Hammer, R E, Hobbs, H H, Young, S G
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 1993
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC288508/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8254057/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116927
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