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Inhibition of class II phosphoinositide 3-kinase γ expression by p185(Bcr-Abl) contributes to impaired chemotaxis and aberrant homing of leukemic cells
Expression of p185(Bcr-Abl) in Ba/F3 cells inhibits chemotactic response of these cells to SDF1α. A mutant p185(Bcr-Abl) with deletion of amino acids from 176 to 426 (p185(Δ176–426)) is deficient in suppressing SDF1α-stimulated chemotaxis. Comparison of the gene expression profiles among parental Ba...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2885034/ https://ncbi.nlm.nih.gov/pubmed/20536348 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/10428191003754624 |
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