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BCR-ABL Induces Abnormal Cytoskeleton Remodeling, β1 Integrin Clustering, and Increased Cell Adhesion to Fibronectin Through ABL Interactor 1 Pathway

Hematopoietic cells isolated from patients with Bcr-Abl-positive leukemia exhibit multiple abnormalities of cytoskeletal and integrin function. These abnormalities are thought to play a role in the pathogenesis of leukemia; however, the molecular events leading to these abnormalities are not fully u...

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Hlavní autoři: Li, Yingzhu, Clough, Nancy, Sun, Xiaolin, Yu, Weidong, Abbott, Brian L., Hogan, Christopher J., Dai, Zonghan
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1950936/
https://ncbi.nlm.nih.gov/pubmed/17389688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.03430
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