Differential Interactions of FGFs with Heparan Sulfate Control Gradient Formation and Branching Morphogenesis

The developmental activities of morphogens are controlled by the gradients that they form in the extracellular matrix (ECM). In this report, we show that differences in the binding of fibroblast growth factor 7 (FGF7) and FGF10 to heparan sulfate (HS) underlie the formation of different gradients th...

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Библиографические подробности
Главные авторы: Makarenkova, Helen P., Hoffman, Matthew P., Beenken, Andrew, Eliseenkova, Anna V., Meech, Robyn, Tsau, Cindy, Patel, Vaishali N., Lang, Richard A., Mohammadi, Moosa
Формат: Artigo
Язык:Inglês
Опубликовано: 2009
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2884999/
https://ncbi.nlm.nih.gov/pubmed/19755711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2000304
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