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Local delivery of beta interferon using an adeno-associated virus type 5 effectively inhibits adjuvant arthritis in rats

Beta interferon (IFN-β) is a cytokine with potent immunomodulatory properties and has been described as a promising therapeutic molecule for the treatment of rheumatoid arthritis (RA). IFN-β was previously overexpressed intra-articularly using an adenoviral vector in rats with adjuvant arthritis (AA...

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Hlavní autoři: Adriaansen, J., Fallaux, F. J., de Cortie, C. J., Vervoordeldonk, M. J., Tak, P. P.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for General Microbiology 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2884954/
https://ncbi.nlm.nih.gov/pubmed/17485531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/vir.0.82603-0
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