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Experimental determination of translational starts using peptide mass mapping and tandem mass spectrometry within the proteome of Mycobacterium tuberculosis

Identification of protein translation start sites is largely a bioinformatics exercise, with relatively few confirmed by N-terminal sequencing. Translation start site determination is critical for defining both the protein sequence and the upstream DNA which may contain regulatory motifs. It is demo...

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Detalhes bibliográficos
Main Authors: Rison, Stuart C. G., Mattow, Jens, Jungblut, Peter R., Stoker, Neil G.
Formato: Artigo
Idioma:Inglês
Publicado em: Microbiology Society 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2884946/
https://ncbi.nlm.nih.gov/pubmed/17259624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/mic.0.2006/001537-0
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